Description:

NANOMATERIALS FOR INTEGRATION OF SOFT INTO HARD TISSUES

INV-13090

INVENTORS: Daniel J. Hickey, Thomas J. Webster, Batur Ercan

 

Description       

None of the existing technologies/mechanisms allow regeneration of tendon-to-bone insertion site using nanotechnology. Moreover, only few biodegradable polymers are available. However, none of them provides an improved three-dimensional cell-matrix network formation. This invention discloses a novel polymer composite scaffold, to be used as a biodegradable orthopedic implant to regenerate inhomogeneous orthopedic tissues, potentially addressing prior-art limitations and unmet needs.

 

 

Value Proposition

The polymer scaffold:

• Is nano-structured

• Effectively mimics the extra-cellular body matrix

• Is ring-shaped, allowing orthopedic soft tissue to pass through the center

• Is mineralized with specialized nanoparticles to increase bone and ligament growth

• Effectively provides an improved three-dimensional cell-matrix network formation as compared to existing polymers

• Would be commercially useful for the following applications:

o Biodegradable orthopedic implant for Joint reconstructive surgeries

o Improved connection of a ligament graft to bone in case of orthopedic surgeries

o Growth promotion for inhomogeneous tissues

 

 

Intellectual Property status

Provisional Application 61/827,164

 

License status

Available for license

 

Patent Information:
For Information, Contact:
Mark Saulich
Associate Director of Commercialization
Northeastern University
m.saulich@northeastern.edu
Inventors:
Srinivas Sridhar
Rajiv Kumar
Wilfred Ngwa
Gerassimos Makrigiorgos
Robert Cormack
Keywords:
Antimicrobial
Biotech
Health
Healthcare Innovation
Nanomedicine
Nanotechnology