Antibiotic resistance is a predicament that affects more than 2 million people worldwide each year. Through the over-prescription and extensive use of antibiotics, bacteria have generated resistance to many common antibiotic treatments. A promising approach to target antibiotic-resistant bacteria is the use of metallic nanoparticles. 
Technology Overview
In this invention, an environmentally safe synthesis of tellurium nanoparticles is used. Rod-shaped tellurium nanoparticles coated with polyvinylpyrrolidone (PVP) were prepared using a facile hydrothermal reduction reaction. Transmission electron microscopy (TEM) images were used to characterize the size and morphology of the nanoparticles and showed a narrow size distribution. Energy-dispersive X-ray spectroscopy (EDS) was performed to verify the chemical composition of the nanoparticles. 
These nanoparticles possess both anti-cancer and antibacterial effects without being toxic to healthy cells. 
- The nanorods show no significant cytotoxicity against healthy human dermal fibroblasts at concentrations up to 100 µg/mL
- Can produce highly functional nanoparticles using less extreme operating conditions than traditional synthesis methods and without producing toxic byproducts 
- Antibacterial coatings for medical equipment 
- Antibacterial coatings for pipes 
- Antibacterial treatment for healthcare-acquired infections (HAIs) 
- Cancer therapeutic applications
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For Information, Contact:
Vaibhav Saini
Senior Manager Commercialization
Northeastern University
Christopher Brown
Amit Roy
Thomas Webster
David Medina Cruz
Analytical Chemistry